Name

HFTD3, Dutch-III

Phenotype

Frontotemporal Dementia (Autopsy Proven)

Inheritance

Autosomal Dominant

Onset Age

Mean: 61.2 years; Range: 53 - 71 years; 10 patients

Age at Death

Mean: 70.7 years; Range: 63 - 78 years

Disease Duration

Mean: 8.6 years; Range: 6 - 13 years

Ethnic origin

Caucasian (The Netherlands)

Mutation

GRN Ser82fs (Segregation Proven)

Citations

Rosso SM, Brain 124: 1948-1957, 2001
Bronner IF, European Journal of Human Genetics 15: 369-374, 2007

Added: January 24, 2007

ID: 654